ANCA-Associated Vasculitis in Patient with CREST-Syndrome - Case Report

Citation: Zakharova EV, Makarova TA, Stolyarevich ES (2016) ANCA-Associated Vasculitis in Patient with CREST-Syndrome Case Report. Arch Clin Nephrol 2(1): 049-052. 049 the European League Against Rheumatism in 2013, defined the following classification criteria: skin thickening of the fingers of both hands extending proximally to the metacarpophalangeal joints; skin thickening of the fingers; fingertip lesions; telangiectasia; abnormal nailfold capillaries; pulmonary arterial hypertension and/or interstitial lung disease; Raynaud phenomenon; and systemic sclerosis–related autoantibodies (anticentromere, anti–topoisomerase I and anti–RNA polymerase III). Renal involvement, though it is not rare and might be life-threatening, was not included into the list of classification criteria [2]. CREST syndrome (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasias), although not all are needed for the disorder to be called CREST, is an older term used to describe this subset of limited systemic sclerosis, formerly named scleroderma [3].